
GMP-grade Reagent Production
![]() RESEARCH GRADE (IPSWICH, MA, USA) |
![]() GMP GRADE (ROWLEY, MA, USA) |
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MANUFACTURING PROCESSES |
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PRODUCT ATTRIBUTES |
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QA & REGULATORY |
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"GMP-grade" is a branding term NEB uses to describe reagents manufactured at NEB’s Rowley facility. The Rowley facility was designed to manufacture reagents under more rigorous infrastructure and process controls to achieve more stringent product specifications and customer requirements. Reagents manufactured at NEB’s Rowley facility are manufactured in compliance with ISO 9001 and ISO 13485 quality management system standards. However, at this time, NEB does not manufacture or sell products known as Active Pharmaceutical Ingredients (APIs), nor does NEB manufacture its products in compliance with all of the Current Good Manufacturing Practice regulations.
This content is covered by patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc. For more information, please email us at [email protected]. The use of these products may require you to obtain additional third party intellectual property rights for certain applications.
Product portfolio
NEB manufactures and inventories the following enzyme specificities at GMP-grade, meeting customer needs with short lead times. Learn more about our GMP-grade IVT reagents.
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Vaccinia Capping Enzyme A full system for enzymatic capping based on the Vaccinia virus Capping Enzyme (VCE) |
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RNase Inhibitor, Murine
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RNA Polymerase used for in vitro mRNA synthesis, and is highly specific for the T7 phage promoter.
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COMING SOON: Hi-T7 RNA Polymerase RNA Polymerase designed for in vitro transcription of RNA at higher temperatures.
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Pyrophosphatase, Inorganic (E. coli) Inorganic pyrophosphatase (PPase) catalyzes the hydrolysis of inorganic pyrophosphate to form orthophosphate. |
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mRNA Cap 2´-O-Methyltransferase mRNA Cap 2´-O-Methyltransferase adds a methyl group at the 2´-O position of the first nucleotide adjacent to the cap structure at the 5´ end of the RNA. |
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DNase I (RNase-free) DNA-specific endonuclease used for removal of contaminating genomic DNA from RNA samples and degradation of DNA templates in transcription reactions. |